Pfizer - Bothell, WA

posted about 1 month ago

Full-time - Senior
Bothell, WA
Chemical Manufacturing

About the position

The Director of the Bioanalytical team at Pfizer's Oncology Research Unit (ORU) will lead efforts in characterizing large and small molecules within the Antibody-Drug Conjugate (ADC) Discovery organization. This role is pivotal in advancing the discovery of novel ADCs for cancer treatment, focusing on enhancing technological capabilities and collaborating with senior members of the ADC Discovery Research Group to drive Pfizer's ADC strategy and preclinical pipeline.

Responsibilities

  • Lead a team of 6+ scientists, including PhD-level professionals.
  • Create and manage sub-team prioritization efforts to ensure optimal portfolio progression and scientific rigor.
  • Develop strategies to improve capacity and efficiency of platform technologies through innovation and application of new technologies.
  • Leverage new technologies and existing bioanalytical approaches to characterize protein biologics and ADC mechanisms of action.
  • Work closely with early Research and Process Sciences departments to balance priorities and ensure efficient transfer of knowledge and processes.
  • Represent the team in governance forums and advocate for the team's visibility.
  • Provide supervision and mentorship, establishing the vision and enabling personal growth of team members.
  • Promote a culture of professionalism and collaboration focused on patient outcomes.

Requirements

  • Ph.D. in Biochemistry, Chemistry, or related discipline.
  • Minimum 7+ years with Ph.D. or 9+ years post MS related oncology or chemistry experience in industry.
  • Expertise in ADCs, including understanding of drug linker and small molecule biochemical conjugation.
  • Expertise in protein-protein and small molecule binding kinetics using BLI or SPR technologies.
  • Expertise in analytical method development for various biotherapeutic modalities.
  • Deep understanding of antibody binding behavior with antigens and Fc receptors, including FcRn.
  • Technical expertise in mass spectrometry for both large and small molecules across various vendor platforms.
  • CMC experience in project progression from research to development.
  • Deep experience in building, leading, and directly managing teams.

Nice-to-haves

  • Strong track record of scientific accomplishments in industry as evidenced by publications or other equivalent achievements.
  • Experience getting results through creativity and unique problem solving.

Benefits

  • 401(k) plan with Pfizer Matching Contributions
  • Paid vacation, holiday, and personal days
  • Paid caregiver/parental and medical leave
  • Health benefits including medical, prescription drug, dental, and vision coverage
Job Description Matching

Match and compare your resume to any job description

Start Matching
© 2024 Teal Labs, Inc
Privacy PolicyTerms of Service