Research Associate II - Zhang Lab

Broad Institute - Cambridge, MA

Full-time - Mid Level

Cambridge, MA

Professional, Scientific, and Technical Services

About the position

The Research Associate II position at the Zhang Lab of the Broad Institute is a full-time role focused on developing programmable therapeutics to enhance human health. The lab emphasizes innovative research, particularly in engineering physiology using animal models. The successful candidate will engage in various laboratory techniques, collaborate with a dynamic team, and contribute to impactful scientific discoveries.

Responsibilities

• Manage the Zhang lab mouse colony, including maintaining an inventory system for the lab as well as breeding and genotyping animals
• Perform routine mouse procedures, including blood collection, surgeries, and behavioral assays
• Maintain procedure room for animal work
• Design and execute research plans, analyze data, and communicate scientific results to team members at regular project update meetings
• Perform molecular biology techniques, including nucleic acid purification, molecular cloning, DNA/RNA purification, PCR, and gel electrophoresis
• Develop and execute cell-based assays to validate delivery vehicles both in vitro and in vivo
• Prepare next generation sequencing libraries and analyze the results
• Work dynamically and flexibly with team members to move projects forward, and pitch in around lab when needed
• Troubleshoot scientific problems with guidance
• Prepare, order, and maintain stocks of necessary reagents and supplies

Requirements

• A bachelor's degree in molecular/cellular biology, neurobiology, chemistry, or a related field with lab experience
• Experience working with mice
• Ability to critically read, interpret, and adapt scientific literature
• Strong organization, documentation, and time management skills
• Ability to build excellent working relationships and foster collaboration in a team environment

Benefits

• Health insurance
• Dental insurance
• Vision insurance
• Opportunities for advancement
• Retirement plan