Research Associate Position, Cardiovascular Institute (CVI) - Zoltan Arany, MD, PhD Laboratory

University of Pennsylvania - Philadelphia, PA

Full-time - Entry Level

Philadelphia, PA

Educational Services

About the position

The Division of Cardiovascular Medicine in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania is seeking candidates for several Research Associate positions within the Cardiovascular Institute (CVI) laboratory led by Zoltan Arany, MD, PhD. This full-time position is initially offered for one year, with the possibility of renewal based on satisfactory performance and the availability of funding, limited to a total of three years. Candidates must possess a Ph.D. degree to be eligible for this role. The Research Associate will engage in a variety of scientific experiments utilizing mouse models to explore development, pathology, and injury related to cardiovascular health. Key responsibilities include maintaining a mouse colony of transgenic animals, generating new alleles through CRISPR technology and murine stem cell targeting, and conducting molecular biology experiments focused on vascular biology. This includes investigating mechanisms of vascular malformations, heart disease, lymphatic and blood vessel development, as well as COVID-19-related vascular pathologies. In addition to experimental work, the Research Associate will play a crucial role in mentoring graduate students and technicians, contributing to the lab by introducing new techniques, and participating in the writing and submission of manuscripts. The position also involves applying for external funding and presenting research findings at both internal lab meetings and external conferences. The successful candidate will have the opportunity to drive research projects, submit proposals, and secure independent funding, while collaborating with other investigators within the Perelman School of Medicine and external institutions. This role is designed to enhance the candidate's bench-top skills, mentorship experience, team management capabilities, and grant and manuscript writing skills. The University of Pennsylvania values diversity and encourages applications from individuals of diverse backgrounds, including minorities, women, individuals with disabilities, and protected veterans.

Responsibilities

• Perform scientific experiments using mouse models of development, pathology, and injury.
• Maintain a mouse colony of transgenic animals.
• Generate new alleles using CRISPR and murine stem cell targeting.
• Conduct molecular biology experiments to study vascular biology, including mechanisms of vascular malformations and heart disease.
• Investigate lymphatic and blood vessel development and COVID-19-related vascular pathologies.
• Assist in bench training of graduate students and technicians.
• Introduce new techniques to the lab.
• Read and write manuscripts for publication.
• Apply for external funding and secure independent funding.
• Present research work at internal lab meetings and external conferences.

Requirements

• Ph.D. degree in a relevant field.
• Experience with mouse models and molecular biology techniques.
• Strong background in vascular biology and related research areas.

Nice-to-haves

• Experience with CRISPR technology.
• Previous mentoring experience with graduate students or technicians.
• Familiarity with grant writing and manuscript preparation.

Benefits

• Opportunity to broaden bench-top skills.
• Mentorship experience.
• Experience managing teams.
• Skill development in grant-writing and manuscript-writing.