University of Minnesota - Minneapolis, MN

posted 4 days ago

Full-time - Entry Level
Minneapolis, MN
Educational Services

About the position

The Minnesota Muscle Lab is seeking a Researcher 3 to coordinate and assist with projects focused on early-phase drug discovery and translational research for heart disease and muscle disorders. This role involves leading biosensor development and cell culture for multiple NIH-funded projects, utilizing advanced techniques in molecular dynamics and spectroscopy to understand muscle health and disease.

Responsibilities

  • Plan, design, and generate recombinant DNA constructs for creating stable clones using various molecular biology techniques.
  • Characterize expression via western blot and flow cytometry, and maintain a recombinant DNA database.
  • Plan and design expression strategies for new cell lines expressing novel proteins, and maintain stable cell lines in HEK cells.
  • Prepare reconstituted fluorescently-labeled membrane proteins and perform microplate-based assays for drug discovery.
  • Conduct basic maintenance of laboratory equipment, order supplies, and present research findings at meetings.

Requirements

  • BA/BS in Biology, Biochemistry, Genetics, or related field plus two years of research lab experience, or a combination of education and work experience totaling six years.
  • Previous mammalian tissue culture experience.
  • Laboratory experience with common molecular biology techniques including site-directed mutagenesis, cloning, primer design, enzyme assays, and reagent preparation.
  • Ability to carry out research protocols from written or oral instructions.

Nice-to-haves

  • Extensive experience with nucleotide sequence analysis and challenging cloning projects.
  • Experience with HEK cells and flow cytometry.

Benefits

  • Competitive wages, paid holidays, and generous time off.
  • Continuous learning opportunities through professional training and degree-seeking programs.
  • Low-cost medical, dental, and pharmacy plans.
  • Healthcare and dependent care flexible spending accounts.
  • University HSA contributions.
  • Disability and employer-paid life insurance.
  • Employee wellbeing program.
  • Excellent retirement plans with employer contribution.
  • Public Service Loan Forgiveness (PSLF) opportunity.
  • Financial counseling services.
  • Employee Assistance Program with eight sessions of counseling at no cost.
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