University of Colorado - Aurora, CO

posted 6 months ago

Full-time - Mid Level
Aurora, CO
Educational Services

About the position

The University of Colorado Anschutz Medical Campus is seeking a Senior Research Associate to join the Department of Cell & Developmental Biology. This position is integral to a project focused on understanding the cellular and molecular mechanisms of chemotherapy-induced taste disruption. The successful candidate will engage in a variety of research activities, including the in vitro culture of taste organoids and conducting experiments with laboratory mice. The role requires maintaining a mouse colony, treating both mice and organoids with pharmacological agents, and performing various laboratory techniques such as cryosectioning, immunohistochemistry, and gene expression analysis using qRT-PCR and Hybridization Chain Reaction (HCR). Additionally, the candidate will be responsible for data collection, entry, analysis, and meticulous record-keeping. The Senior Research Associate will also manage lab responsibilities, which include purchasing supplies, maintaining equipment, and scheduling necessary service and calibration. A key aspect of this role is to assist in training and mentoring students and new staff, fostering a collaborative and educational environment within the lab. The position is expected to work onsite in Aurora, CO, and will report directly to the Principal Investigator, Dr. Linda Barlow, a Professor in the Cell and Developmental Biology department. This role offers an exciting opportunity to contribute to cutting-edge research in a supportive and dynamic academic setting.

Responsibilities

  • Assist with a project aiming to understand the cellular and molecular mechanisms of chemotherapy-induced taste disruption.
  • Perform in vitro culture of taste organoids and experiments involving laboratory mice.
  • Maintain the mouse colony.
  • Treat mice and organoids with pharmacological agents.
  • Manage lab responsibilities including purchasing, maintenance of equipment and supplies, and scheduling service/calibration.
  • Assist with training and mentoring students and new staff.

Requirements

  • MD/PhD with emphasis in biology, chemistry, genetics, or related field.
  • At least 5 years' experience in biological research.
  • High level of knowledge of tissue preparation, cell cultures, and tissue sectioning.
  • Proficiency in animal care related to research procedures, including managing a mouse colony with complex breeding strategies and timely genotyping.
  • Expert in confocal and light microscopy and accompanying software.
  • Experience in validating the quality of data and obtaining quantitative data.
  • Experience in writing data analysis and experimental methods and procedures for research manuscripts.

Nice-to-haves

  • Ability to work independently
  • Ability to create and innovate
  • Ability to multi-task
  • Ability to communicate effectively both written and orally
  • Ability to set priorities and schedule work effectively.

Benefits

  • Generous leave
  • Health plans
  • Retirement contributions
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