Assistant Research Professor in Dr. Pelosis lab

Indiana University - Indiana, PA

Full-time - Entry Level

Indiana, PA

Ambulatory Health Care Services

About the position

The Pelosi Lab at Indiana University School of Medicine is seeking a highly motivated Research Professor (non-tenure track) at the Assistant level for a project related to the genomics of reproductive conditions and reproductive development. This position will primarily involve working with genetically modified mice, including the collection, isolation, and culturing of cells and tissues, as well as employing molecular biology techniques to study factors involved in cell differentiation and development. The ideal candidate will possess strong organizational and interpersonal skills to conduct experiments, contribute to the preparation of manuscripts and grant proposals, and participate in weekly laboratory meetings to present and discuss findings. More specifically, the Assistant Research Professor will be responsible for planning and coordinating highly detailed in vivo and in vitro experiments using genetically modified mice, which will include histological and gene expression analyses. As the Pelosi Lab is part of an international consortium, the candidate will have the opportunity to connect with several national and international collaborators and collaborate with IU core facilities to complete downstream assays such as single-cell RNA sequencing, spatial transcriptomics, and genome editing of mouse models using CRISPR. Other applications routinely performed in the Pelosi lab include tissue embedding and sectioning, immunofluorescence, microscopy, qPCR, cloning, and bioinformatic analyses. We are looking for an enthusiastic candidate who is eager to learn and work in the fields of molecular biology, developmental biology, genetics, and reproduction. The ideal candidate will have excellent verbal and written communication skills, be fluent in English, and exhibit good organization skills, creativity, and intellectual curiosity. IUSM is committed to being an institution that reflects the learners we teach and the patient populations we serve, pursuing the values of equity and inclusion that inform academic excellence. We desire candidates whose work contributes to equitable and inclusive learning and working environments for our learners, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana.

Responsibilities

• Plan and coordinate in vivo and in vitro experiments using genetically modified mice.
• Conduct histological and gene expression analyses.
• Connect with national and international collaborators as part of an international consortium.
• Collaborate with IU core facilities to complete downstream assays such as single-cell RNA sequencing and spatial transcriptomics.
• Perform genome editing of mouse models using CRISPR.
• Engage in tissue embedding and sectioning, immunofluorescence, microscopy, qPCR, cloning, and bioinformatic analyses.
• Contribute to the preparation of manuscripts and grant proposals.
• Participate in weekly laboratory meetings to present and discuss findings.

Requirements

• Doctorate degree in biomedical sciences or related field required.
• Experience working with mice, including mouse handling and dissection, and management of breeding colonies.
• Expertise in molecular/cell biology.

Nice-to-haves

• Extensive experience in mammalian tissue culture systems including 3D/organoids is preferred and considered a plus.