Bristol-Myers Squibb - San Diego, CA

posted 5 days ago

Full-time - Senior
Hybrid - San Diego, CA
Chemical Manufacturing

About the position

The Associate Director in Discovery Toxicology at Bristol-Myers Squibb plays a crucial role in the Pharmaceutical Candidate Optimization organization, focusing on identifying and addressing toxicology issues across discovery programs. This position involves collaboration with cross-functional teams to ensure the advancement of high-quality drug candidates into development, utilizing expertise in drug metabolism, pharmacokinetics, and toxicology.

Responsibilities

  • Assess and develop plans for evaluating potential toxicity of new drug targets.
  • Apply appropriate models and testing strategies that inform on mechanisms of toxicity, addressing relevance to humans.
  • Design, conduct, interpret toxicology studies within drug discovery and communicate results across multiple disciplines.
  • Participate in drug discovery teams as a toxicology expert, communicating issues and experimental strategies for resolution.
  • Contribute to the collective research expertise in Discovery Toxicology, including laboratory efforts to advance new tools for mechanistic toxicology research.
  • Discuss and enable the transition of drug candidates into the BMS Development organization.

Requirements

  • Bachelor's Degree with 12+ years of academic/industry experience, or a Master's Degree with 10+ years of experience, or a PhD with 8+ years of experience and 4+ years of leadership experience.
  • A Ph.D. in toxicology or a related field with postdoctoral experience is preferred.
  • Broad-based knowledge of toxicology, particularly in investigating molecular mechanisms of toxicity.
  • Experience in computational toxicology, systems pharmacology, or metabolism-mediated toxicity is desired.
  • Strong communication skills, both verbal and written, are essential.

Nice-to-haves

  • Experience in drug discovery within the pharmaceutical industry.
  • Ability to design in vivo studies across species.
  • Demonstrable skill set in design and implementation of mechanistic toxicology studies.

Benefits

  • Paid holidays
  • Disability insurance
  • Health insurance
  • Dental insurance
  • Tuition reimbursement
  • Military leave
  • Employee assistance program
  • Life insurance
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