Associate Director Discovery Toxicology

$22,000 - $178,000/Yr

Bristol-Myers Squibb - Cambridge, MA

Full-time - Senior

Hybrid - Cambridge, MA

Chemical Manufacturing

About the position

The Associate Director in Discovery Toxicology at Bristol-Myers Squibb plays a crucial role in the Pharmaceutical Candidate Optimization organization, focusing on identifying and addressing toxicology issues across discovery programs. This position involves collaboration with cross-functional teams to ensure the advancement of high-quality drug candidates into development, utilizing expertise in drug metabolism, pharmacokinetics, and toxicology.

Responsibilities

• Assess and develop plans for evaluating potential toxicity of new drug targets.
• Apply appropriate models and testing strategies that inform on mechanisms of toxicity, addressing relevance to humans.
• Design, conduct, interpret toxicology studies within drug discovery and communicate results across multiple disciplines.
• Participate in drug discovery teams as a toxicology expert, communicating issues and experimental strategies for resolution.
• Contribute to the collective research expertise in Discovery Toxicology, including laboratory efforts to advance new tools for mechanistic toxicology research.
• Discuss and enable the transition of drug candidates into the BMS Development organization.

Requirements

• Bachelor's Degree with 12+ years of academic/industry experience, or Master's Degree with 10+ years, or PhD with 8+ years of academic/industry experience and 4+ years of leadership experience.
• A Ph.D. in toxicology or related field with postdoctoral experience and 8+ years in the pharmaceutical industry, preferably in drug discovery.
• Broad-based knowledge of toxicology, emphasizing molecular mechanisms of toxicity.
• Experience in computational toxicology, systems pharmacology, or metabolism-mediated toxicity.
• Strong communication skills, both verbal and written.
• Ability to work collaboratively with an enterprise mindset and patient-focused values.

Nice-to-haves

• Experience in designing in vivo studies across species.
• Demonstrable skill set in design and implementation of mechanistic toxicology studies.

Benefits

• Paid holidays
• Disability insurance
• Health insurance
• Dental insurance
• Tuition reimbursement
• Military leave
• Employee assistance program
• Life insurance