United Therapeutics Corporation - Durham, NC

posted about 1 month ago

Full-time - Mid Level
Durham, NC
Professional, Scientific, and Technical Services

About the position

The Associate Scientist in Analytical Development at United Therapeutics plays a crucial role in conducting research to support the development of tissue-engineered lungs. This position focuses on evaluating the health and function of engineered lung tissue, particularly the behavior and function of vascular endothelial cells, through various bioanalytical assays. The role involves collaboration across teams, data analysis, and contributing to scientific communications, all aimed at advancing the company's mission to find cures for life-threatening diseases.

Responsibilities

  • Conduct research to support the development of tissue-engineered lungs.
  • Evaluate the health and function of engineered lung tissue with a focus on vascular endothelium using bioanalytical assays.
  • Perform bioanalytical assays to characterize cellular behavior and engineered lung function.
  • Analyze and interpret results, making insightful recommendations.
  • Analyze single cell RNA sequencing or spatial transcriptomics data.
  • Develop and optimize mono and co-culture cell-based assays.
  • Participate in cross-team collaborations to support the characterization of critical primary lung cell types.
  • Evaluate circulating molecules to establish in-process metrics of engineered tissue health.
  • Conduct independent literature reviews and propose experimental plans.
  • Execute laboratory experiments with attention to detail and strong record-keeping.
  • Analyze data and compile findings into summary reports.
  • Prepare presentations and discuss data with laboratory staff and external partners.
  • Contribute to the writing and review of scientific communications.

Requirements

  • Bachelor's Degree in biology, molecular biology, cell & molecular biology, or a related discipline.
  • 5+ years of relevant industry experience with a Bachelor's Degree, or 3+ years with a Master's Degree, or 1+ years with a PhD.
  • 4+ years of experience performing bioanalytical assays (flow cytometry, ELISA, qPCR).
  • 1+ year of experience with data analysis software (FCS Express, FlowJo, Graphpad Prism, FIJI).
  • Ability to independently follow experimental methods and protocols.
  • Proficient with laboratory instrumentation and data analysis software.
  • Excellent verbal and written communication skills.
  • Highly self-motivated and able to collaborate with others.

Nice-to-haves

  • Master's Degree or PhD in biology, molecular biology, cell & molecular biology, or a related discipline.
  • 1+ years of relevant industry experience in the development of biologics for therapeutics.

Benefits

  • Paid parental leave
  • Employee stock purchase plan
  • Disability insurance
  • Health insurance
  • Dental insurance
  • Paid time off
  • Vision insurance
  • Prescription drug insurance
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