Associate Scientist, Downstream Process Development and Manufacturing

$95,000 - $120,000/Yr

Dren Bio - Foster City, CA

Full-time - Entry Level

Foster City, CA

About the position

The Associate Scientist in Downstream Process Development and Manufacturing at Dren Bio will play a crucial role in the development and optimization of purification processes for therapeutic antibodies. This position involves working closely with the Downstream Process Development group to ensure the successful scale-up and transfer of processes to contract manufacturing organizations (CMOs), as well as providing technical support during manufacturing operations. The role requires a strong background in protein purification techniques and the ability to work independently in a fast-paced environment.

Responsibilities

• Develop and scale-up robust multi-step purification processes
• Design and execute drug substance formulation studies
• Present experimental data in project and group meetings
• Author technical reports
• Implement new purification technologies to optimize and streamline processes
• Transfer and oversee purification process at CMO for GMP manufacturing
• Review executed batch records from CMO manufacturing
• Produce material for in-house development

Requirements

• Bachelors or Masters degree in Chemistry, Biochemistry or related scientific field
• 4+ years of relevant industry experience for MS and 6+ years for BS level candidates
• Experienced in protein purification techniques including column chromatography, standard membrane filtration and Ultrafiltration/Diafiltration
• Working knowledge of AKTA systems and Unicorn programming
• Ability to analyze and interpret complex process data
• Strong interpersonal skills and excellent oral and written communication skills

Nice-to-haves

• Ability to travel and perform Person-in-Plant manufacturing oversight at a CMO
• Experience working with external manufacturing vendors and partners

Benefits

• Competitive cash compensation
• Equity incentive awards
• Employer sponsored benefit offerings