Computational Systems Biologist/Engineer

Battelle - Columbus, OH

Full-time - Entry Level

Columbus, OH

Professional, Scientific, and Technical Services

About the position

Battelle is seeking a highly skilled and motivated Computational Systems Biologist to join the National Security Business Unit in Columbus, Ohio. This full-time role involves conducting cutting-edge research in computational biology, systems biology, and metabolic modeling. The successful candidate will provide technical leadership in modeling and predicting regulatory networks and metabolic changes, while collaborating with a multidisciplinary team to advance scientific knowledge in protein biochemistry.

Responsibilities

• Conduct combined modeling and experimental campaigns to predict and model microbial metabolism and improve microbial strains for biomanufacturing.
• Assist with the development of genome scale models of biomanufacturing microbial strains.
• Work independently to meet study or campaign objectives and deliverables with some oversight.
• Collaborate with analytical chemists and biologists to design and develop experiments to understand microbial and plant metabolism.
• Integrate large data sets into models of biological systems.
• Analyze and interpret experimental data, contributing to technical reports, scientific manuscripts, and presentations.
• Train and mentor junior technical staff.
• Travel domestically and potentially internationally as required.

Requirements

• PhD in biochemistry or a related field with 0-4+ years of experience.
• Expertise in metabolic modeling and genome scale modeling approaches such as COBRApy and OptKnock.
• Experience in developing and refining systems biology-based models of biochemical reaction networks.
• Proficiency in scripting and coding using R, Python, and/or Bash/Unix shell.
• Excellent problem-solving skills, critical thinking abilities, and attention to detail.
• Strong communication and interpersonal skills for collaborative work.
• Ability to travel as needed.
• Sufficient medical fitness to work in laboratory and field environments.
• U.S. citizenship with the ability to obtain and maintain required government security clearances.

Nice-to-haves

• Experience in artificial intelligence and machine learning approaches involving biological systems.
• Experience working within laboratory quality management systems (e.g., ISO 9001, ISO17025, GLP).
• Experience with high-throughput automation equipment and data sets derived from these systems.

Benefits

• Flexible, compressed work schedule allowing for every other Friday off.
• Paid time off to support work-life balance.
• Medical, dental, and vision coverage with wellness incentives.
• Coverage for partners, gender-affirming care, and family formation support.
• 401(k) retirement savings plan with employer contributions and matching.
• Tuition assistance for higher education pursuits.
• Flexible work arrangements for location and hours.