Director, Functional Genomics

Vesalius Therapeutics - Cambridge, MA

Full-time - Senior

Cambridge, MA

About the position

Vesalius Therapeutics is seeking a highly motivated and collaborative Director of Functional Genomics to lead the discovery of new therapeutic targets and develop world-class target discovery platforms. This role involves assembling and leading a team with expertise in molecular biology, cell biology, cell engineering, assay development, and new technology development, with a focus on innovative approaches such as CRISPR screening and high-throughput protein interaction assays.

Responsibilities

• Design, develop and implement medium and high throughput functional genomic screens in cell lines, primary cells, and reprogrammed stem cell cultures.
• Evaluate and introduce new genome-scale technologies to the company, and champion their use in our discovery efforts.
• Be a strong voice in the development and implementation of our target discovery platform.
• Assemble and lead a team of skilled scientists to execute this mission, and collaborate across our diverse group of scientific disciplines to develop new ideas.

Requirements

• PhD in a biological discipline with at least 8-10 years of relevant experience in an industry or academic setting. Additional qualifications, including MD, strongly preferred.
• An outstanding reputation in your field as a creative scientist, a technology innovator, and as a dynamic leader, evidenced by publication track record and/or patent filings.
• Deep expertise in cell and molecular biology and experience with state-of-the-art functional genomics screening technologies including contemporary expertise with CRISPR technologies used for genome-wide screens.
• Extensive experience with cell-based assay development and screening using a variety of readout technologies.
• Strong quantitative intuition, excellent data analysis and data mining skills, and experience and comfort with laboratory automation.
• Direct supervisory experience (5+ years) leading a team of scientists (including PhD-level scientists) and a track record of recruiting, mentoring, and developing top talent.
• Outstanding communication, collaboration, networking, and program leadership skills.
• Demonstrated ability to work in a dynamic environment with a sense of urgency and creativity and focus on deliverables.
• Team player with a strong work ethic, able to work both independently and collaboratively.
• Continuously learns and adapts quickly to new information.
• Authentic, proactively appreciative of different points of view, backgrounds and perspectives.