Immunitybio - El Segundo, CA

posted 4 months ago

Full-time - Mid Level
El Segundo, CA
Administrative and Support Services

About the position

As part of the Engineering Team, the Facilities Process Engineer II is responsible for maintaining, troubleshooting, and improving existing process equipment, overseeing the selection, procurement, and installation of new equipment, and assisting with projects to expand facilities in FDA regulated biopharmaceutical environments. This role requires close collaboration with facilities maintenance, GMP manufacturing, quality operations, leadership, and other functions to ensure successful ongoing manufacturing operations while also expanding those operations. The engineer will effectively interact and collaborate with cross-functional departments to meet company expectations and serve as a subject matter expert for assigned processes, equipment, and utilities. The Facilities Process Engineer II will manage small projects that require internal function oversight, developing project scope and timelines, and assist with multiple larger projects by representing engineering in a dynamic and changing environment. Responsibilities include identifying appropriate vendors and contractors, developing requests for proposals, managing the onboarding of new vendors, troubleshooting and coordinating investigations of manufacturing and laboratory processes, and leading teams to address deviations and non-conformances by performing root cause analysis. The engineer will also develop and implement preventive actions and corrective actions, author and review SOPs, protocols, and change controls, and mentor junior engineers or technicians on engineering policies and requirements to support GMPs. Additionally, the engineer will lead engineering design reviews as needed, collaborate with clients, contract manufacturers, and vendors to meet project and company objectives, and participate in audits and regulatory agency inspections as required. This position is critical in ensuring that the facilities and processes are compliant with regulatory standards and that the engineering team is well-equipped to handle the challenges of a biopharmaceutical environment.

Responsibilities

  • Maintain, troubleshoot, and improve existing process equipment.
  • Oversee the selection, procurement, and installation of new equipment.
  • Assist with projects to expand facilities in FDA regulated biopharmaceutical environments.
  • Collaborate with cross-functional departments to meet company expectations.
  • Serve as subject matter expert for assigned processes, equipment, and utilities.
  • Manage small projects requiring internal function oversight, developing project scope and timelines.
  • Assist with larger projects by representing engineering in a dynamic environment.
  • Identify appropriate vendors/contractors and manage the onboarding process.
  • Troubleshoot and coordinate investigations of manufacturing and laboratory processes.
  • Lead teams to address deviations and non-conformances by performing root cause analysis.
  • Develop and implement preventive actions and corrective actions.
  • Author and review SOPs, protocols, and change controls.
  • Mentor, coach, and train junior engineers or technicians on engineering policies and requirements.
  • Lead engineering design reviews as needed.
  • Collaborate with clients, contract manufacturers, and vendors to meet project and company objectives.
  • Participate in audits and regulatory agency inspections.

Requirements

  • Bachelor's degree in Engineering or other technical discipline with 2-5 years of relevant work experience.
  • Pharma/Biotech industry experience preferred.
  • Good Manufacturing Practices (GMP) experience is required.
  • Operations support in a GMP manufacturing environment.
  • Experience with equipment/process troubleshooting and repair.
  • Experience with facility and equipment commissioning and validation is preferred.
  • Experienced in developing project scope, project budget, and ability to lead small projects is beneficial.

Nice-to-haves

  • Experience with commissioning, IQ/OQ/PQs for GMP equipment and facilities.
  • Knowledge of related quality systems such as change control; CAPA (including deviations/OOSs); training and document control.
  • Working knowledge of GMP, OSHA compliance, 21 CFR Part 11 and cleanrooms, automated biopharmaceutical processing, and plant equipment.

Benefits

  • Medical, Dental and Vision Plan Options
  • Health and Financial Wellness Programs
  • Employer Assistance Program (EAP)
  • Company Paid and Voluntary Life/AD&D, Short-Term and Long-Term Disability
  • Healthcare and Dependent Care Flexible Spending Accounts
  • 401(k) Retirement Plan with Company Match
  • 529 Education Savings Program
  • Voluntary Legal Services, Identity Theft Protection, Pet Insurance and Employee Discounts, Rewards and Perks
  • Paid Time Off (PTO) includes: 11 Holidays, Unlimited PTO for Exempt Employees, 10 Vacation Days, 56 Hours of Health Pay, 2 Personal Days and 1 Cultural Day.
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