Head of Cancer Biology

Dewpoint Therapeutics - Boston, MA

Full-time - Senior

Hybrid - Boston, MA

Professional, Scientific, and Technical Services

About the position

Dewpoint Therapeutics is seeking an experienced and visionary Head of Cancer Biology to lead their Cancer Biology team. This leadership role, which may be leveled at either Senior Director or Vice President, is pivotal in driving the discovery of novel oncology therapeutics. The incumbent will oversee cancer biology research efforts, focusing on innovation, scientific excellence, program execution, and cross-functional collaboration. The role involves managing oncology research projects from target identification to candidate nomination, ensuring alignment with organizational goals, and fostering a collaborative research environment.

Responsibilities

• Drive the strategic direction of the Cancer Biology function, ensuring alignment with broader organizational goals.
• Lead and mentor a high-performing team of scientists and researchers, fostering a collaborative and innovative research environment.
• Direct the distribution of team efforts and deadlines to ensure seamless progress of experiments and fulfillment of goals across various initiatives.
• Oversee the design, execution, and analysis of efforts required for successful small molecule drug candidate nomination.
• Serve as the primary lead for generating DC-enabling data packages in collaboration with chemists, biologists, and other leads.
• Drive the design, execution, compilation, examination, and summarization of in vivo pharmacology studies.
• Enhance and standardize in vivo cancer models and protocols, adhering to regulatory, ethical, and quality standards.
• Promote employee engagement and professional development within the team.
• Manage the progression of oncology research projects, ensuring timely execution and delivery of key milestones.
• Stay abreast of advancements in oncology research, particularly in cancer biology and drug discovery.
• Drive innovation within the Cancer Biology team by encouraging exploration of new models and methodologies.
• Forge and sustain collaborations with CROs, industry peers, and academic bodies as needed.
• Assist in writing and contributing to scientific documents for regulatory filings and presentations.

Requirements

• Ph.D. or MD/Ph.D. in cancer biology or related field of science.
• At least 10 years of relevant experience, including small molecule discovery.
• Demonstrated end-to-end oncology drug discovery expertise with a track record of delivering development candidates.
• Deep knowledge of oncology, including current and emerging standards of care.
• Experienced in the creation and use of diverse in vivo cancer models for efficacy and PK/PD studies.
• Strong leadership and people management skills, fostering a collaborative team culture.
• Exceptional communication skills to convey complex scientific concepts to various audiences.
• Ability to work effectively in a highly matrixed and dynamic environment.

Nice-to-haves

• Experience with cell line engineering, humanized models, or surgical/resection models.
• Familiarity with regulatory guidelines and Good Laboratory Practice (GLP) standards.
• Experience with bioinformatics tools relevant to pharmacology and oncology research.

Benefits

• Competitive salary
• Great benefits
• Amazing perks