Manager, Clinical Supply Chain

$131,000 - $162,333/Yr

Denali Therapeutics - South San Francisco, CA

posted 3 months ago

Full-time - Mid Level
South San Francisco, CA
Professional, Scientific, and Technical Services

About the position

Denali Therapeutics is seeking a Manager for the Clinical Supply Chain to join our team in South San Francisco. This role is pivotal in ensuring the effective production and distribution of therapies aimed at treating neurodegenerative diseases, which represent one of the most significant medical challenges today. As a biotechnology company, Denali is dedicated to developing breakthrough therapies through a deep commitment to degeneration biology and translational medicine. The successful candidate will work closely with the Clinical Supply Chain Planning Lead to monitor and enhance production and distribution strategies for various clinical programs. In this position, you will serve as the primary point of contact for Supply Chain Execution, collaborating with internal stakeholders such as Supply Chain, Quality Assurance (QA), and Clinical Operations. You will oversee Denali's Finished Product supply chain vendors, facilitating execution activities that include contracts, product setup, labeling, packaging, distribution, and inventory management. Your responsibilities will also encompass facilitating label development, approval, and tracking, as well as managing the issuance and tracking of QP Declaration and Certification. Additionally, you will document and execute IRT transactions necessary for the release and distribution of products through the clinical supply chain. Investigating exceptions to determine root causes, implementing Corrective and Preventive Actions (CAPAs), and driving closure will be key aspects of your role. You will proactively identify and troubleshoot issues to prevent missed timelines and communicate the status of supply execution activities through both verbal and written reports. Continuous operational performance improvement efforts will be a focus, and you will participate in supply chain business process development projects to enhance efficiency and effectiveness.

Responsibilities

  • Partner with Clinical Supply Chain Planning Lead to monitor the production and distribution strategies for their respective programs
  • Serve as Supply Chain Execution point of contact with internal stakeholders (i.e. Supply Chain, QA, Clinical Operations)
  • Provide oversight to Denali's Finished Product supply chain vendors and facilitate execution activities (i.e. Contracts, Product Set Up, Labeling, Packaging, Distribution, Inventory Management)
  • Facilitate Label development, approval, and tracking
  • Facilitate QP Declaration and Certification issuance and tracking
  • Document and execute IRT transactions required to facilitate the release and distribution of product through the clinical supply chain
  • Responsible for investigation of exceptions to determine root causes, implement CAPAs and drive closure
  • Proactively identify and troubleshoot issues to prevent missed timelines
  • Communicate status of supply execution activities both verbally and through written documents and reports
  • Drive continuous operational performance improvement efforts
  • Participate in supply chain business process development projects

Requirements

  • Bachelor's degree in Industrial Engineering/Operations/Supply Chain or related field
  • 3+ years experience in clinical supply chain management or manufacturing in the Life Sciences
  • Experience in vendor oversight and managing external partnerships and relations is preferred
  • Experience working on cross functional projects and business process definition/improvements is preferred
  • Knowledge of IRT system setup and functionality is preferred
  • Demonstrated ability to work accurately, meet timelines and handle multiple priorities
  • Skilled in using influence management to drive project success
  • Capable of responding flexibly to changing prioritization in a dynamic environment
  • Strong interpersonal skills and ability to work with others in a positive 'can do' and collaborative manner
  • Strong verbal and written communication skills
  • Proficiency in MS Excel, Word, and PowerPoint
  • Requires working knowledge of cGMP and regulations applicable to the FDA and comparable international regulatory agencies.

Nice-to-haves

  • Experience in vendor oversight and managing external partnerships and relations
  • Experience working on cross functional projects and business process definition/improvements
  • Knowledge of IRT system setup and functionality

Benefits

  • 401k
  • healthcare coverage
  • Employee Stock Purchase Plan (ESPP)
  • broad range of other benefits
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