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Neuroscientist
Science - Alameda, CA
posted 3 days ago
About the position
Science is a clinical stage, vertically integrated technology company focused on solving some of neuroscience's hardest questions and most serious unmet medical needs. We work to restore quality of life to those with debilitating conditions for which there are no treatment options, creating devices aimed at restoring vision, cognition, and mobility to patients who have lost it. To support progress across our industry, we provide state-of-the-art components and vertically integrated infrastructure for others to build on via Science Foundry. We are developing a biohybrid brain-computer interface to increase the number of interface channels by several orders of magnitude. We are extending our pilot work on this subject, recently posted on bioRxiv, to develop a fully integrated cell-device hybrid that can potentially achieve over a million single-unit interface channels with the brain. We are looking for experimental neuroscientists enthusiastic about performing collaborative research to develop a transformative approach to brain-computer interfaces.
Responsibilities
- Perform cranial surgical implants for studies on graft integration and device development
- Perform in vivo electrophysiology with both commercial and custom brain probes
- Perform and analyze live 2P imaging to assess graft survival, integration, and activity develop strategies to promote neuron graft survival and integration
- Develop experimental approaches to test physiology of graft integration
- Develop strategies to promote graft survival
- Analyze experiments and present results
Requirements
- A track record of excellence and creativity in your field as demonstrated by publications, patents, success with commercialization or translation, or other notable achievements
- Expert level proficiency with rodent cranial surgeries and aseptic techniques, including installation of cranial windows and intracortical injections
- Expert level proficiency working with conventional in vivo electrophysiology probes (e.g. neuropixels)
- Expert level proficiency working with scientific computing packages to control online experimental control and analyze data
- Thrives when working collaboratively and tackling difficult technical challenges
- Excellent communication skills
- Commitment to a respectful and supportive work environment
Nice-to-haves
- PhD in Neuroscience
- Proficiency with mammalian cell culture
- Direct experience transplanting stem cells into the nervous system
- Practical experience with histopathology materials and methods
- Experience training animals and performing quantitative animal behavior experiments
Benefits
- Competitive salary and equity
- Medical, dental, vision and life insurance
- Flexible vacation and company-paid holidays
- Healthy meals and snacks provided for non-remote employees
- Paid parental, jury duty, bereavement, family care and medical leave
- Dependent Care Flexible Spending Account, subsidized by Science
- Flexible Spending Account
- 401(k)
