Parenteral Formulation Characterization, Sr. Principal Scientist
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About The Position
Vertex is seeking a talented individual to join our Analytical Development Department in Boston, MA. We are looking for a candidate with both leadership skills and a strong technical experience in physiochemical/biophysical characterization of peptides, oligonucleotides, and small molecule drug substances and associated parenteral drug products (e.g., glass vials, prefilled syringes, aqueous liquid, lyophilized powder/cake, frozen solutions etc.) and advanced pharmaceutical drug delivery technologies (e.g., cyclodextrin inclusion complex, polymeric/lipid nanoparticles, etc.). The candidate must be a strong team player with excellent oral and written communication skills working in a complex cross-functional matrix. The Analytical Development Senior Principal Research Scientist will collaborate closely with associate CMC functions and act as a subject matter expert in physiochemical and biophysical characterization of drug substances and parenteral drug products. This role will lead the physical and biophysical characterization of parenteral drug products and includes both establishing standard and developing novel characterization techniques for small molecule, peptide and oligonucleotide in complex parenteral dosage forms. The successful candidate must be able to work independently and collaborate in a fast-paced, integrated, multidisciplinary team environment and be able to develop novel and creative solutions to overcome project obstacles and make significant conceptual contributions to project teams. The role will be involved in projects from exploratory development through various clinical stages to regulatory filing.
