Unclassified - Columbia, MO
posted 4 months ago
The Immunomodulation and Translational Research Program in the Department of Pediatrics at the University of Missouri, Columbia, MO, is seeking to fill three open positions at the Postdoctoral or Research Scientist levels. These roles are integral to federally funded projects that focus on cancer immunoprevention and immunotherapy. The program has made significant strides in developing novel immune ligands, demonstrating their therapeutic efficacy across various cancer types. A notable highlight is the biologic SA-4-1BBL, which has shown prophylactic efficacy against multiple tumor types by activating an immune surveillance mechanism. This groundbreaking observation is the first of its kind and holds substantial translational potential for cancer treatment. The selected candidates will delve into the mechanistic underpinnings of SA-4-1BBL in cancer immunoprevention and will work on discovering new targetable pathways to create a universal cancer immunoprevention platform aimed at high-risk individuals. We are particularly interested in applicants who possess extensive conceptual knowledge and practical expertise in immunology, cancer immunotherapy, and mouse models of cancer, including humanized models. Hands-on experience in immune cell functional assays and flow cytometry is also essential. We are looking for self-motivated and innovative individuals who have ambitious career goals. Our expanding program provides exceptional opportunities for postdocs and research scientists to grow and achieve their career objectives. The program is situated in the NextGen building, which features state-of-the-art facilities and an outstanding research environment that promotes interactions, collaborations, and career development.