Principal Scientist, Early Translational Computational Science for Immunology, Cardiovascular and Neurology

$119,000 - $149,000/Yr

Bristol-Myers Squibb - Cambridge, MA

Full-time - Mid Level

Hybrid - Cambridge, MA

Chemical Manufacturing

About the position

The role of a computational scientist at Bristol Myers Squibb involves addressing translational questions within the Immunology, Cardiovascular, and Neurology Early Translational team. The position focuses on applying advanced bioinformatics techniques to analyze multi-omic and clinical datasets, aiming to identify biomarkers that can inform drug development and enhance patient outcomes. This position is integral to the company's mission of driving transformative insights for patient benefit through innovative computational research.

Responsibilities

• Analyze various -omic-scale biomarker data generated from human subjects in clinical trials and other observational cohorts, including RNA-Seq, Exome, and Whole Genome Sequencing, high throughput proteomics, and multiplex flow cytometry.
• Conduct analysis independently to integrate and mine large-scale external datasets to further our understanding of diseases in Immunology and Neurology.
• Work both independently and collaboratively to extract insights, generate hypotheses and guide drug development decisions in our Early Clinical, Development and Translational teams.

Requirements

• Bachelor's Degree with 8+ years of academic/industry experience, or Master's Degree with 6+ years of academic/industry experience, or PhD with 4+ years of academic/industry experience.
• Proficiency using R required and 1+ additional programming language preferred.
• Strong experience in statistical modeling and/or machine learning approaches, such as mixed-effects models, predictive modeling, etc.
• Individual contributor role requiring strong background in -omic (DNA, RNA, epigenetic, proteomic) data analysis and biological interpretation.

Nice-to-haves

• Ph.D. in bioinformatics, molecular biology, genetics, engineering, statistics, or a similar discipline.
• Four (4) or more years relevant experience in preclinical or clinical research.
• Experience with clinical database (SDTM/ADaM) and biomarker statistical analysis is a plus.
• Prior experience in immunology or neurology is a plus.

Benefits

• Medical, pharmacy, dental and vision care.
• Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP).
• Financial well-being resources and a 401(K).
• Short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support.
• Paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility.
• Parental, caregiver, bereavement, and military leave.
• Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources.
• Tuition reimbursement and a recognition program.