Research Assistant

Avexo Pharmaceuticals - Watertown, MA

Full-time

Watertown, MA

About the position

The Research Assistant position is designed for a motivated individual with a strong background in molecular biology and assay development. This role is essential for supporting the research team in early-stage product development, involving hands-on laboratory work and collaboration with a small, interdisciplinary team of scientists.

Responsibilities

• Conduct molecular biology experiments, including DNA/RNA extraction, PCR, cloning, and gene expression analysis.
• Develop and optimize assays to support ongoing research projects, ensuring high sensitivity, specificity, and reproducibility.
• Maintain and troubleshoot mammalian and/or bacterial cell cultures, following sterile techniques and ensuring cell line viability and quality.
• Perform protein expression and purification tasks, including the use of chromatography, filtration, and centrifugation techniques.
• Prepare buffers, reagents, and media required for assays and cell culture work.
• Analyze experimental data, maintain accurate lab records, and present findings in team meetings.
• Collaborate with cross-functional team members to support the design, implementation, and optimization of research protocols.
• Contribute to lab maintenance, including ordering supplies, organizing samples, and maintaining equipment.

Requirements

• Bachelor's or Master's degree in Molecular Biology, Biochemistry, Biotechnology, or a related field.
• 1-3 years of hands-on experience in a research setting, preferably within a biotech or life sciences startup.
• Proficiency in molecular biology techniques such as PCR, qPCR, cloning, and gel electrophoresis.
• Experience with mammalian and/or bacterial cell culture, including cell line maintenance, transfection, and viability assays.
• Knowledge of protein purification techniques (e.g., affinity, ion-exchange, size-exclusion chromatography) and experience using related equipment (e.g., AKTA).
• Familiarity with assay development, including ELISA, reporter assays, and fluorescence-based assays.
• Proficient in data analysis software (e.g., Excel, GraphPad Prism) and able to use standard lab information management systems.
• Strong attention to detail, excellent organizational skills, and the ability to work both independently and in a team.