Research Associate, Analytical Science

$71,200 - $106,800/Yr

AstraZeneca - Santa Monica, CA

Full-time - Entry Level

Santa Monica, CA

1,001-5,000 employees

Chemical Manufacturing

About the position

The Research Associate, Analytical Science will be responsible for managing routine testing and contributing to daily operational tasks within the Analytical Science team. This role focuses on characterizing engineered T cell therapy processes and products through various analytical methods and supports the overall lab operations.

Responsibilities

• Perform routine analytical testing for cell culture/passaging, immunophenotyping using multi-parametric flow cytometry, plate-based immunoassays, and luminescent-based cell functional assays.
• Work with Analytical method developers and quality control personnel to improve test methods, draft SOPs and other documents.
• Document test method performance parameters as part of the method monitoring program.
• Support everyday lab operations of analytical laboratories, including critical reagent qualification, equipment management, and reagent inventory.
• Maintain, calibrate, and operate analytical equipment and instrumentation used for routine execution.
• Complete laboratory tasks or experiments as assigned and report results by assigned deadlines.
• Support projects with Process Development and Quality groups.

Requirements

• BS degree in Biochemistry, Cell Biology, or related discipline with 1+ years of relevant experience, or Master's degree in Immunology, Molecular Biology, or relevant field.
• Experience in mammalian cell culture is required.
• Demonstrate proficiency with implementing plate-based immunoassays (e.g. ELISA, ELLA, Luminex, AlphaLISA).
• Experience with mammalian cell-based potency assays (e.g. co-culture, cytotoxicity, proliferation) and multi-color flow cytometry (e.g. BD Fortessa, BD Lyrics, or BD Symphony).
• Excellent skills with using Microsoft Excel, Word, and PowerPoint in a scientific environment.
• Experience using data analysis software (e.g. Prism, JMP, FACSDiva, FlowJo, CytEpert, FCS Express SoftMax Pro).
• Experience working in the cell therapy area.
• Experience with Good Documentation Practices and routine testing execution in a regulated environment (e.g. GMP, GLP, or CLIA).

Benefits

• 401(k)
• Dental insurance
• Health insurance
• Paid holidays
• Vision insurance