Calidi Biotherapeutics - San Diego, CA

posted 10 days ago

Full-time - Mid Level
San Diego, CA
Professional, Scientific, and Technical Services

About the position

The IN VIVO Research Associate at Calidi Biotherapeutics plays a crucial role in conducting research and development projects focused on immuno-oncology. This position involves performing in vivo studies, analyzing data, and interpreting results related to the efficacy of oncolytic viruses in various cancer models. The role requires collaboration with team members and adherence to safety and compliance protocols while maintaining accurate records of experiments.

Responsibilities

  • Perform in vivo studies to evaluate efficacy in murine models
  • Administer test substances by various routes (i.e., intratumoral, IP, IV, SC, PO, topical, etc.)
  • Perform mouse necropsies, tissue harvest, and mouse blood collection via cardiac puncture, submandibular, retro orbital, etc.
  • Model pre-clinical tumors
  • Handle and dose animals (Intratumoral, IP, IV, PO, and SC), bleeding, necropsy, and tissue harvest
  • Perform in vivo imaging to monitor tumor growth (IVIS or equivalent)
  • Manage and observe animals for general health and overall well-being
  • Independently perform all methods and conduct all study types commonly employed by the team
  • Maintain accurate experiment records in various internal databases and perform basic data analysis
  • Adhere to good health and safety practices and compliance with applicable EH&S rules and participate in mandatory safety training programs
  • Adhere to SOPs to ensure study integrity and quality

Requirements

  • 2+ years of experience in an animal laboratory setting
  • Good organizational and documentation skills
  • Dedication to working in a team-oriented environment to contribute to shared projects
  • Strong work ethic, self-motivation, and ability to multi-task in a fast-paced work environment
  • Strong knowledge of MS Word, Outlook, PowerPoint, Excel
  • Ability to work with mathematical concepts such as calculation of dilutions and statistical analyses
  • Excellent communication skills with the ability to effectively communicate with other research teams
  • Ability to read and understand technical procedures
  • Ability to write protocols and reports
  • Ability to effectively present data and respond to questions from co-workers

Nice-to-haves

  • Experience in qPCR, ELISA, immuno-oncology, TIL isolation, and flow cytometry

Benefits

  • Health insurance
  • Dental insurance
  • Vision insurance
  • 401(k) matching
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