RESEARCH SCIENTIST/ENGR 1

$48,000 - $78,000/Yr

University of Washington - Bothell, WA

Full-time - Entry Level

Bothell, WA

Educational Services

About the position

The Research Scientist/Engineer 1 position at the University of Washington's Institute for Protein Design (IPD) involves making significant contributions to protein design research. The role focuses on developing new research methods, collecting experimental data, and interpreting results in collaboration with other scientists. The position is part of the Core R&D Labs, specifically within the Biologics, Vaccines, Production, and Process Development Research Core, where the emphasis is on producing biologics and vaccines for various therapeutic indications.

Responsibilities

• Produce proteins utilizing microbial systems with standard production techniques.
• Produce proteins utilizing mammalian cell systems with standard production techniques.
• Purification of proteins using high-throughput autosamplers in conjunction with AKTA FLPCs.
• Characterize proteins using biophysical techniques such as SDS-PAGE, Western Blot, UV-Vis, Dynamic Light Scattering (DLS), High Performance Liquid Chromatography (HPLC), and Electron Microscopy (EM).
• Review, analyze, and troubleshoot all experimental results.
• Document protocols run in the wet lab.
• Follow standard operating procedures and working guidelines.
• Mentor IPD researchers on Core-specific workflow.
• Work directly with Principal Investigators, postdoctoral fellows, graduate students, and laboratory staff in assisting with and conducting experiments.
• Maintain databases and inventories, including preparation and maintenance of standard laboratory stocks and reagents.
• Maintain inventory for all chemicals, supplies, reagents, and biological samples.
• Maintain and troubleshoot laboratory equipment.
• Assist with laboratory-wide EH&S compliance.
• Assist with managing undergraduate research assistants.
• Present scientific data, attend meetings and team-building events.

Requirements

• Bachelor's Degree in Biochemistry, Molecular Biology, or any other relevant field and one year experience with protein expression and characterization using biophysical techniques, OR equivalent combination of education/experience.
• Experience with protein expression in microbial systems like E.coli using IPTG and autoinduction.
• Development and optimization of purification methods for gravity and FPLC assisted IMAC, IEX.
• Characterize proteins using biophysical techniques by SDS-PAGE, Western Blot, UV-Vis, DLS, HPLC and EM.
• Strong communication and organization skills and great attention to detail.
• Ability to thrive in both individual tasks and team environments/assignments.
• A willingness to acquire new skills and learn on the job.

Nice-to-haves

• One or more years of relevant protein biochemistry experience in a laboratory setting.
• Hands-on experience with protein purification systems and equipment.

Benefits

• Generous benefits and work/life programs.
• Professional growth opportunities.
• Unique resources in a diverse and intellectually stimulating environment.