Novartis - Cambridge, MA

posted 3 days ago

Full-time - Mid Level
Cambridge, MA
Chemical Manufacturing

About the position

Novartis Oncology Biotherapeutics is seeking a passionate Scientist to advance biotherapeutic drug discovery for cancer. This role is ideal for a motivated individual with expertise in drug discovery for oncology, cancer immunology, or immunotherapy. The successful candidate will play a key role in developing treatments that impact patient lives.

Responsibilities

  • Design and conduct in vitro assays to screen candidate immune cell-engaging (ICE) antibodies or biologics
  • Analyze and interpret data to advance projects through the discovery pipeline
  • Explore and validate new drug targets
  • Utilize automation and high-throughput systems for large-scale ICE antibody screening
  • Document experimental results in electronic lab notebooks
  • Present research findings in internal and external meetings
  • Solve complex problems and optimize procedures to meet team goals

Requirements

  • Bachelor's degree with 2-3 years of experience (industry or academia) or master's degree with 0-1 years (industry or academia) in cancer immunotherapy, cancer biology, molecular biology, or related fields for Research Scientist II
  • Bachelor's degree with 3-4 years (industry or academia) or master's degree with 1-2 years (industry or academia) in cancer immunotherapy, cancer biology, molecular biology, or related fields for Senior Scientist I
  • Strong knowledge of immuno-oncology, immunology, or cell or molecular biology
  • Hands-on experience with immune cell isolation, in vitro cell assays, and molecular techniques (e.g., cell line generation, MSD, RT-qPCR, lentiviral transduction, cell culture)
  • Proficient in functional immune cell assays, including proliferation, phenotype profiling, cytokine profiling, or cytotoxicity assays
  • Excellent documentation, data analysis, and presentation skills
  • Strong communication and teamwork abilities

Nice-to-haves

  • Industry experience in antibody or biologics drug discovery
  • Experience with high-throughput instruments and multi-color flow cytometry
  • Skills in lentiviral transduction and western blotting
  • Experience with immune cell culture and assays

Benefits

  • 401(k) eligibility
  • Various paid time off benefits, such as vacation, sick time, and parental leave
  • Sign-on bonus
  • Restricted stock units
  • Discretionary awards
  • Full range of medical and financial benefits
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