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Scientist III, Chemistry
$75,000 - $120,000/Yr
Quantum-Si Incorporated - Guilford, CT
posted 2 days ago
Full-time - Mid Level
Guilford, CT
Publishing Industries
About the position
We are seeking a highly skilled and motivated chemist to join our dynamic reagent development team. The successful candidate will play a crucial role in designing, optimizing, and implementing oligonucleotide-based bioconjugation processes. The ideal candidate should have a strong background in nucleic acid chemistry, bioconjugation chemistry, and analytical methods.
Responsibilities
- Plan and execute solid-phase oligonucleotide synthesis.
- Design, optimize, and validate bioconjugation processes for the conjugation of oligonucleotides to fluorescent dyes, peptides, and proteins.
- Work collaboratively with cross-functional teams to integrate chemical processes into overall project timelines.
- Stay abreast of the latest advancements in bioconjugation methodologies and technologies.
- Develop and implement new methodologies and technologies to enhance bioconjugation efficiency, scalability, and reproducibility.
- Utilize a variety of analytical techniques to characterize oligonucleotides and bioconjugates, including HPLC, mass spectrometry, spectroscopy, and other relevant methods.
- Ensure the development of robust analytical methods for assessing bioconjugation product quality.
- Collaborate with interdisciplinary teams, including biochemists, biologists, and engineers, to achieve project goals.
- Clearly communicate experimental designs, results, and interpretations to both technical and non-technical stakeholders.
- Maintain accurate and detailed records of experiments, results, and protocols.
- Ensure compliance with relevant regulatory guidelines and company policies.
Requirements
- PhD in chemistry or MS with 3+ years of relevant industrial experience is required.
- Track record of scientific publication/patent application.
- Expertise in solid-phase oligonucleotide synthesis is required.
- Proficiency in a wide range of analytical techniques to characterize biopolymers, with a focus on HPLC, mass spectrometry, and other relevant methods.
- Excellent communication skills, both written and verbal, to effectively convey complex scientific concepts to diverse audiences.
Nice-to-haves
- Experience with oligonucleotide-protein conjugates.
Benefits
- Discretionary bonus program
- Equity as part of the compensation package
