(Senior) Research Associate, In Vitro, Cell and Molecular Biology

Job Application For Research Associate / Senior Research Associate, Vaccine Researchflagship Pioneering, Inc. - Cambridge, MA

Full-time - Mid Level

Cambridge, MA

About the position

FL106 Inc. is seeking a highly motivated (Senior) Research Associate with expertise in Cell and Molecular Biology to contribute to the validation of novel target discovery approaches. This role is crucial for the growth of an early-stage biotechnology company focused on developing groundbreaking genetic medicine technologies. The ideal candidate will thrive in a dynamic environment, demonstrating independence, goal orientation, and excellent communication skills.

Responsibilities

• Generate and maintain mammalian cell culture lines and perform downstream experiments using novel platform-generated compounds.
• Perform high-throughput nucleic acid and/or protein isolation from cell and animal tissues using standard and automated systems (e.g. Kingfisher, Qiacube, etc).
• Develop and validate downstream assays (e.g. qRT-PCR, flow cytometry, ELISA) for key readouts of platform-generated compounds.
• Collaborate with team to develop experimental plans, document results in an ELN, and make presentations to report findings to team.
• Work as a key contributor on cross-functional teams including chemistry and in vivo pharmacology.

Requirements

• Bachelor's degree in Biology or a related field, with 1+ years of laboratory experience preferably in bio-pharmaceutical industry.
• Strong experience with nucleic acid (DNA/RNA) isolation from mammalian cells and tissues, cDNA synthesis, and qRT-PCR is essential.
• Hands-on experience in mammalian cell culture and using various delivery technologies (e.g. transfection, nucleofection, etc).
• Experience with developing assays using various readout technologies including qRT-PCR, ELISA, and flow cytometry.
• Experience with various ELN and LIMS systems.
• Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.

Nice-to-haves

• Animal (mouse/rat) handling, take-down, and tissue collection.
• In vivo procedures: IV, RO, IP injections.