Third Rock Ventures - Lexington, MA
posted 4 days ago
About the position
Voyager Therapeutics, Inc. is seeking an experienced and highly motivated biologist to contribute to our biochemical and in vivo research team at our facility in Lexington, Massachusetts. This position is ideal for an individual with an in vivo biology background and biochemical/molecular biology methods, who thrives in a team-oriented, fast-paced, and cross-disciplinary small biotech environment. The individual will work at the bench on multiple projects and be responsible for experimental execution and data analysis for research studies supporting therapeutic programs and platform discovery research. We are looking for prior hands-on experience with protein purification, ELISA, western blot, mouse handling, perfusion and tissue collection.
Responsibilities
- Support of rodent in vivo experiments, animal handling, and test article dosing via various administration routes (IP, IM, IV etc). Experience with stereotactic brain surgery is preferred
- Rodent perfusion, necropsy, dissection, and tissue collection including serum & CSF collection
- Ex vivo tissue analysis (tissue processing, protein purification, ELISA, western blot, RT-qPCR, etc.), DNA isolation, and independent data analyses
- Experience in In vitro cell culture and transfection, as well as in imaging
- Closely collaborate with research scientist to execute in vivo studies utilizing rodent models to support AAV-based gene therapy research and development for neurodegenerative diseases
- Perform biochemical and tissue-based assays to support project development and target validation
Requirements
- A minimum of a Bachelor's degree with 5+ years' experience or a Master's degree with 2+ years' experience or equivalent in neuroscience, cell culture, biomedical sciences, animal sciences or related discipline
- Outstanding problem-solving skills
- Understanding of biological safety and animal welfare practices and regulations
- Self-motivated, trustworthy, and ability to be highly productive in a fluid, collaborative, and fast-paced team environment
- Outstanding problem-solving skills
- Experience with design, documentation, and execution of experiments
- Ability to be highly productive in a fluid and fast-paced work environment
- Scientific and team-directed communication skills
- Must be organized and efficient in processing samples and performing analyses on a consistent schedule
Nice-to-haves
- Experience with animal handling
- Experience on cross-functional therapeutic program teams
- Experience within a start-up or small biotech environment
